High Wycombe is surrounded by some of the most lovely countryside in southern England. The Chiltern Hills are officially designated an Area of Outstanding Natural Beauty and are easily accessible by car and public transport, and through hundreds of miles of public footpaths including the long-distance Ridgeway Path.

The town in situated in a deep valley, in the heart of the Chilterns. To the south, the M40 connects the town to London, the M25 and Heathrow Airport while to the north the M40 leads to Birmingham and the Midlands. There is a fast rail link to London Marylebone (45 minutes) and half-hourly trains to Warwick, Stratford-upon-Avon and Birmingham. Oxford is under an hour away by coach.